Effects of Blood Collection Conditions on Ovarian Cancer Serum Markers
نویسندگان
چکیده
منابع مشابه
Effects of Blood Collection Conditions on Ovarian Cancer Serum Markers
BACKGROUND Evaluating diagnostic and early detection biomarkers requires comparing serum protein concentrations among biosamples ascertained from subjects with and without cancer. Efforts are generally made to standardize blood processing and storage conditions for cases and controls, but blood sample collection conditions cannot be completely controlled. For example, blood samples from cases a...
متن کاملProteomics Analysis for Finding Serum Markers of Ovarian Cancer
A combination of peptide ligand library beads (PLLB) and 1D gel liquid chromatography-mass spectrometry/mass spectrometry (1DGel-LC-MS/MS) was employed to analyze serum samples from patients with ovarian cancer and from healthy controls. Proteomic analysis identified 1200 serum proteins, among which 57 proteins were upregulated and 10 were downregulated in the sera from cancer patients. Retinol...
متن کاملSerum protein markers for early detection of ovarian cancer.
Early diagnosis of epithelial ovarian cancer (EOC) would significantly decrease the morbidity and mortality from this disease but is difficult in the absence of physical symptoms. Here, we report a blood test, based on the simultaneous quantization of four analytes (leptin, prolactin, osteopontin, and insulin-like growth factor-II), that can discriminate between disease-free and EOC patients, i...
متن کاملSystematic Evaluation of Candidate Blood Markers for Detecting Ovarian Cancer
BACKGROUND Epithelial ovarian cancer is a significant cause of mortality both in the United States and worldwide, due largely to the high proportion of cases that present at a late stage, when survival is extremely poor. Early detection of epithelial ovarian cancer, and of the serous subtype in particular, is a promising strategy for saving lives. The low prevalence of ovarian cancer makes the ...
متن کاملBlood and Urine Markers for Ovarian Cancer: A Comprehensive Review
Kathryn L. Terrya, Patrick M. Slussb, Steven J. Skatesc,d, Samuel C. Mokd, Bin Yed, Allison F. Vitonisa and Daniel W. Cramera Ob-Gyn Center Epidemiology Center, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women’s Hospital, Boston, MA, USA Reproductive Endocrinology Unit Laboratory, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA Biostatist...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2007
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0001281